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SIAMETRICS


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Skin measurement, In vivo, In seconds

SIAMETRICS™ allows cosmetic formulators and active ingredient manufacturers to accurately measure and quantify the concentrations of melanin, haemoglobin and collagen in living human skin.

SIAMETRICS is powered by SIAscopy™, a unique patented skin visualisation and measurement technology which gives an accurate, clinically proven* view up to 2mm under the surface of the skin – in vivo.

Data for SIAMETRICS is quickly gathered using the SIAscope, a clinically proven* handheld scanning device. A live view ensures that repeatability of the scan area is achievable, making it possible to build up accurate, valuable data about the structure of the skin, enabling any changes in haemoglobin, melanin or collagen to be quantified.

SIAMETRICS is a standalone application that builds up data over time omitting the need for a database. To help save time and manage your trial effectively SIAMETRICS automatically defines unique file names to SIAscans enabling these to be retrieved and viewed at any time. In conjunction with this SIAMETRICS has the ability to export selected data in a platform independent form for analysis using other tools. Preview greyscale or colour SIAscan images can also be exported for use in promotional materials

SIAMETRICS brings this scientific analysis together with a package to alleviate product trial timescales, making the whole process much easier to manage. With the enhanced information captured in each SIAscan, the whole trial becomes much more valuable, giving a true scientific base to support product claims.


 
       

SIAMETRICS

SIAMETRICS is a powerful skin imaging and measurement system which enables:

  • In-Vivo measurement of the concentrations of melanin, haemoglobin and collagen recording change over time.
  • Accurate measurement of the melanin chromophore. This eliminates the problem of overlap caused by other skin chromophores found in less sophisticated systems.**
  • Captures images and concentrations of all three chromophores in 10 seconds, making trials faster and therefore saving money.
  • Export captured images in a platform independent form. This allows interrogation of SIAscans by sophisticated image analysis software.
  • Intuitive software makes SIAMETRICS simple and quick to use.
  • A live view is provided to ensure repeatable positioning on the skin between iterations.

* Clinical papers are available at www.astronclinica.com
** Reference by Paul J. Matts Ph.D, Jeremy Carey Ph.D & Symon D. Cotton Ph.D (2005) Chromophore Mapping: a New Technique to Characterize Aging Human Skin, In Vivo. American Academy of Dermatology 2005. Paper available to view on www.astronclinica.com

 


Colour view


Haemoglobin view


Melanin view


Collagen view

 
       
 

SIAscopy explained

SIAscopy understands the way that light interacts with the skin; the manner in which it scatters or bounces, the amount absorbed by cells and other structures, along with the different changes in wavelength or colour. By understanding these interactions and comparing the light sent into skin with light that comes back out, SIAscopy is able to determine the nature and position of many of the different components of the skin.

SIAscopy measures key chromophores within the skin, in particular haemoglobin, melanin and collagen. SIAscopy is also able to determine whether melanin is in the top layer of the skin, or whether it has moved lower down into the papillary dermis (dermal melanin).

SIAMETRICS uses the SIAscope V. When the scanner illuminates the skin, some of the light is reflected and scattered from the surface. The remainder is transmitted into the top layers of the skin.

Varying fractions of the incoming light are then firstly absorbed by the melanin in the epidermis before entering the dermis, where they are absorbed by the haemoglobin in the blood vessels. Scattering also occurs in the dermis when the light interacts with the collagen, resulting in a portion of the light being remitted back to the surface.

By interpreting the combination of wavelengths that are received back by the SIAscope V, SIAscopy is then able to produce SIAscans; these are generated by referring to its proprietary mathematical model of skin optics.

 

SIAMETRICS product package contains:

  • SIAscope handheld scanner
  • SIAMETRICS software
  • SIAMETRICS user documentation

Recommended PC Specification for SIAMETRCS

  • Windows XP Professional Operating System
  • 2.0Ghz Pentium 4 processor, or better
  • 2Gb RAM
  • 32Mb graphics memory (DirectX 9 compatible)
  • 250Gb hard disk
  • 1024 x 768 minimum screen resolution
  • 2 x USB 2.0 connections

 

 

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DERMETRICS is based on the Microsoft .NET Framework™ Windows XP™, DirectX™ and Windows Server™. Astron Clinica, DERMETRICS™, SIA, SIAscopy, SIAscanner, SIAscan, SIAscope, SIAscope V, SIAMETRICS, COSMETRICS+, Beau Visage, Beauty Timeline and MoleMate are trade marks of Astron Clinica Limited.

Astron Clinica's products and technology are protected by Patents and Patents pending in the UK, Europe, Australia, USA and other countries worldwide. A list of the Patent and Patent applications owned by Astron Clinica is available on request.

Astron Clinica Limited, The Mount, Toft, Cambridge, CB23 2RL, UK
T. +44 (0) 1223 265 000  F. +44 (0) 1223 264 413  
www.astronclinica.com

Astron Clinica US LLC, 1979 Marcus Avenue, Suite 210, Lake Success, New York, 11042, USA
T.1 516 622 2363  F.1 516 622 2201

Astron Clinica Pty Limited, Christie Centre, 320 Adelaide Street, Brisbane, Qld 4000, Australia
P: +61 (7) 3229 8073 F. +61 (7) 3221 3635 E: ozinfo@astronclinica.com